(4S,4'S)-4,4'-Diisopropyl-1,1'-bis(4-(trifluoromethyl)phenyl)-4,4',5,5'-tetrahydro-1H,1'H-2,2'-biimidazole
97%
science Other reagents with same CAS 2374958-84-4
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description Product Description
Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective organic transformations such as hydrogenation and transfer hydrogenation reactions. Its rigid, sterically hindered structure with defined stereochemistry enables high enantioselectivity when coordinated to transition metals like ruthenium or rhodium. Commonly employed in the synthesis of chiral alcohols and amines, which are key intermediates in pharmaceuticals and fine chemicals. The electron-withdrawing trifluoromethyl groups enhance ligand stability and influence metal center reactivity. Suitable for use in both homogeneous catalytic systems and in the development of chiral catalysts for industrial-scale asymmetric synthesis.
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