Used as a chiral catalyst ligand in asymmetric synthesis, particularly in enantioselective transition metal-catalyzed reactions. Its oxazoline core with defined stereochemistry enhances selectivity in carbon-carbon bond-forming reactions, such as Diels-Alder or Heck reactions. The trifluoromethylpyridine group improves electron-withdrawing properties and coordination stability with metals like palladium or copper, making it effective in promoting high enantiomeric excess. Commonly applied in pharmaceutical intermediates synthesis where stereochemical control is critical.