Used as a chiral auxiliary in asymmetric synthesis, particularly in enantioselective carbon–carbon bond-forming reactions. Its rigid oxazoline rings and stereocenters help control the stereochemistry of reactions, making it valuable in the synthesis of optically active pharmaceuticals and fine chemicals. Commonly employed in coordination with metals like copper or nickel to form catalysts for cyclopropanation, aldol, or Diels–Alder reactions. The isobutyl groups enhance solubility in organic solvents, improving reaction efficiency. After serving its purpose, it can be cleaved and recycled, making it cost-effective for large-scale applications.