Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective organic transformations such as Diels-Alder reactions, aldol additions, and allylic alkylations. Its pyridine-bis(oxazoline) (PYBOX) framework coordinates with metal centers like copper(II) or lanthanides to form highly selective catalysts. The presence of bulky pentan-3-yl and isopropyl substituents enhances stereocontrol by creating a well-defined chiral environment around the metal. This ligand is especially effective in promoting high enantiomeric excess (ee) in carbon–carbon bond-forming reactions, making it valuable in the synthesis of pharmaceuticals and fine chemicals where precise stereochemistry is critical.