Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective organic transformations. Its rigid cyclobutane core and oxazoline rings provide a well-defined chiral environment, making it effective in coordinating to metal centers such as copper or palladium. This complexation enables high enantioselectivity in reactions like cyclopropanations, aldol additions, and Diels-Alder reactions. Due to its stereochemical stability and tunable substituents, it is favored in the synthesis of optically active pharmaceuticals and fine chemicals where precise stereocontrol is critical.