Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the reduction of prochiral olefins, ketones, and imines, delivering high enantiomeric excess (ee) in the presence of transition metal catalysts such as rhodium or ruthenium. Its sterically demanding and electron-withdrawing trifluoromethyl groups enhance both reactivity and selectivity. The rigid ferrocene backbone and well-defined chiral environment make it ideal for use in pharmaceutical synthesis where precise stereochemical control is critical. It is also employed in the development of chiral catalysts for industrial-scale processes due to its stability under various reaction conditions.