(2S,3S)-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2-(2-methoxypropan-2-yl)-2,3-dihydrobenzo[d][1,3]oxaphosphole
97%, 99%ee
Reagent
Code: #233155
CAS Number
2227217-22-1
blur_circular Chemical Specifications
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Molecular Information
Weight
402.47 g/mol
Formula
C₂₃H₃₁O₄P
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Registry Numbers
MDL Number
MFCD34597789
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Storage & Handling
Storage
2-8°C, Sealed, Inert Gas
description Product Description
Used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions such as hydrogenation and cross-coupling. Its rigid backbone and stereogenic centers enable high enantioselectivity, making it valuable in the synthesis of optically active pharmaceuticals and fine chemicals. Commonly employed in palladium- and rhodium-based catalytic systems to control stereochemistry during bond formation. Effective in reactions requiring high steric and electronic tuning due to the electron-donating methoxy groups and bulky tert-butyl and 2-methoxypropan-2-yl substituents.
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