(R)-4-Isopropyl-2-(pyridin-2-ylmethyl)-4,5-dihydrooxazole
97%
Reagent
Code: #232170
CAS Number
2828433-52-7
blur_circular Chemical Specifications
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Molecular Information
Weight
204.27 g/mol
Formula
C₁₂H₁₆N₂O
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Storage & Handling
Storage
2-8°C, Sealed, Dry, Light-proof, Inert Gas
description Product Description
Used as a chiral auxiliary in asymmetric synthesis, particularly in enantioselective carbon-carbon bond-forming reactions. Its rigid oxazoline ring and stereogenic center help control the facial selectivity of nucleophilic additions, making it valuable in the preparation of optically active pharmaceuticals and fine chemicals. Commonly employed in catalytic cycles with transition metals like copper or palladium to promote high enantioselectivity. Also utilized in the synthesis of complex natural products where precise stereochemistry is critical. The pyridine moiety enhances metal coordination, improving catalyst stability and reactivity.
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