Used in asymmetric synthesis as a chiral auxiliary or ligand in catalytic reactions, enabling high enantioselectivity in the formation of carbon-carbon and carbon-heteroatom bonds. Particularly effective in transition metal-catalyzed transformations such as hydrogenations and C–H activation processes. Its rigid proline-based structure enhances stereocontrol, making it valuable in pharmaceutical synthesis where precise chirality is required. Also employed in the development of bioactive molecule precursors and in medicinal chemistry research for designing enzyme inhibitors.