(4R,5R)-4,5-Diphenyl-2-(6-phenylpyridin-2-yl)-4,5-dihydrooxazole
98%, 99%e.e.
Reagent
Code: #231807
CAS Number
2757082-61-2
blur_circular Chemical Specifications
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Molecular Information
Weight
376.45 g/mol
Formula
C₂₆H₂₀N₂O
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Storage & Handling
Storage
2-8°C, Sealed, Dry, Light-proof, Inert Gas
description Product Description
Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective synthesis of pharmaceutical intermediates. Its rigid oxazoline framework enhances stereocontrol in transition metal-catalyzed reactions such as hydrogenation and cyclopropanation. Commonly employed with palladium or copper complexes to achieve high enantiomeric excess in the formation of C–C and C–heteroatom bonds. Valued for its ability to induce chirality in the synthesis of bioactive molecules, including alpha-aryl carbonyl derivatives and nitrogen-containing heterocycles.
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