(R)-2-([2, 2'-Bipyridin]-6-yl)-4-phenyl-4, 5-dihydrooxazole
98%, 99%e.e.
Reagent
Code: #231100
CAS Number
1666123-70-1
blur_circular Chemical Specifications
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Molecular Information
Weight
301.34 g/mol
Formula
C₁₉H₁₅N₃O
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Registry Numbers
MDL Number
MFCD34563663
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Storage & Handling
Storage
2-8°C, dry
description Product Description
Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective transition metal-catalyzed reactions. It plays a key role in promoting stereoselectivity in carbon-carbon bond-forming reactions, such as allylic alkylation and Heck-type reactions. Its rigid oxazoline-bipyridine framework enhances metal coordination control, leading to high enantiomeric excess in the synthesis of pharmaceutical intermediates and fine chemicals. Commonly employed with palladium, nickel, or copper complexes to achieve efficient asymmetric induction under mild reaction conditions.
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