(R)-2-((R)-1-(Diphenylphosphanyl)piperidin-2-yl)-4-isopropyl-4,5-dihydrooxazole

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Reagent Code: #229504
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CAS Number 2757084-62-9

science Other reagents with same CAS 2757084-62-9

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 380.46 g/mol
Formula C₂₃H₂₉N₂OP
thermostat Physical Properties
Boiling Point 496.1±55.0 °C(Predicted)
inventory_2 Storage & Handling
Storage 2-8°C, light-proof, inert gas

description Product Description

Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the synthesis of chiral amines and amino acid derivatives, which are important building blocks in pharmaceuticals. Due to its rigid oxazoline and phosphine groups, it forms stable complexes with transition metals like rhodium and iridium, enhancing catalytic activity and stereoselectivity. Its application extends to the production of active pharmaceutical ingredients (APIs) where high enantiomeric purity is required. The ligand’s structure allows for fine tuning of steric and electronic properties, making it valuable in industrial and academic research for developing efficient asymmetric transformations.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 50mg
10-20 days ฿9,020.00
inventory 100mg
10-20 days ฿14,460.00
inventory 250mg
10-20 days ฿24,550.00

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(R)-2-((R)-1-(Diphenylphosphanyl)piperidin-2-yl)-4-isopropyl-4,5-dihydrooxazole
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Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the synthesis of chiral amines and amino acid derivatives, which are important building blocks in pharmaceuticals. Due to its rigid oxazoline and phosphine groups, it forms stable complexes with transition metals like rhodium and iridium, enhancing catalytic activity and stereoselectivity. Its application extends to the production of active pharmaceutical ingredients (APIs) where high enantiomeric purity is required. The ligand’s structure allows for fine tuning of steric and electronic properties, making it valuable in industrial and academic research for developing efficient asymmetric transformations.
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