(R)-2-((R)-1-(Diphenylphosphanyl)piperidin-2-yl)-4-isopropyl-4,5-dihydrooxazole
97%
Reagent
Code: #229504
CAS Number
2757084-62-9
blur_circular Chemical Specifications
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Molecular Information
Weight
380.46 g/mol
Formula
C₂₃H₂₉N₂OP
thermostat
Physical Properties
Boiling Point
496.1±55.0 °C(Predicted)
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective hydrogenation reactions. It is particularly effective in the synthesis of chiral amines and amino acid derivatives, which are important building blocks in pharmaceuticals. Due to its rigid oxazoline and phosphine groups, it forms stable complexes with transition metals like rhodium and iridium, enhancing catalytic activity and stereoselectivity. Its application extends to the production of active pharmaceutical ingredients (APIs) where high enantiomeric purity is required. The ligand’s structure allows for fine tuning of steric and electronic properties, making it valuable in industrial and academic research for developing efficient asymmetric transformations.
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