(4R,5S)-2-((S)-1-(Diphenylphosphanyl)piperidin-2-yl)-4,5-diphenyl-4,5-dihydrooxazole
97%
Reagent
Code: #229498
CAS Number
2757084-55-0
blur_circular Chemical Specifications
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Molecular Information
Weight
490.58 g/mol
Formula
C₃₂H₃₁N₂OP
thermostat
Physical Properties
Boiling Point
622.1±65.0 °C(Predicted)
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Storage & Handling
Storage
2-8°C, light-proof, inert gas
description Product Description
Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective transformations such as hydrogenation and transfer hydrogenation of prochiral ketones and imines. Its rigid oxazoline-piperidine backbone and diphenylphosphine group make it highly effective in coordinating transition metals like ruthenium, rhodium, and iridium, forming catalysts that deliver high enantiomeric excess. It is particularly valued in pharmaceutical synthesis where precise stereochemical control is critical. The ligand’s structure allows for fine tuning of steric and electronic properties, enhancing selectivity in complex molecule construction.
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