Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective organic transformations. Its rigid cyclobutane core and oxazoline rings provide a well-defined chiral environment, making it effective in coordinating to metal centers such as copper or palladium. This complexation enables high stereoselectivity in reactions like cyclopropanations, aldol additions, and Diels-Alder reactions. The tert-butyl groups enhance steric bulk, improving enantiocontrol. Due to its stability and tunable structure, it is employed in the synthesis of pharmaceuticals and fine chemicals where precise stereochemistry is critical.