Widely used as a chiral ligand in asymmetric catalysis, this compound plays a key role in enantioselective synthesis, particularly in hydrogenation and transfer hydrogenation reactions. It is effective in the preparation of chiral amines and alcohols, which are important intermediates in pharmaceuticals. Due to its rigid biphenyl structure and defined stereochemistry, it provides high enantioselectivity when coordinated with metals like ruthenium, rhodium, or iridium. It is especially valuable in the synthesis of biologically active molecules where control of stereochemistry is critical.