Used as a chiral ligand in asymmetric catalysis, particularly in enantioselective hydrogenation and transfer hydrogenation reactions. Its rigid, well-defined stereochemistry enhances selectivity in the synthesis of chiral amines and alcohols, which are key intermediates in pharmaceuticals. Commonly employed with transition metals like ruthenium or rhodium to form catalytically active complexes. Valued for high enantiomeric excess (ee) in the production of active pharmaceutical ingredients (APIs) and fine chemicals. Also applied in the development of chiral sensors and asymmetric C–C bond-forming reactions.