N,N,N',N'-tetramethyl-BINAM is widely used as a chiral ligand in asymmetric synthesis, particularly in catalytic reactions where enantioselectivity is crucial. It is often employed in metal-catalyzed transformations, such as hydrogenation, cross-coupling, and C-H activation reactions, to produce chiral molecules with high optical purity. Its rigid and well-defined structure makes it effective in controlling the stereochemistry of the reaction products. Additionally, it finds applications in the synthesis of pharmaceuticals and fine chemicals, where the creation of specific enantiomers is essential for biological activity. Its versatility and efficiency in asymmetric catalysis make it a valuable tool in organic synthesis.