Used as a chiral derivatizing agent in asymmetric synthesis, particularly for the preparation of optically active α-amino acids and peptides. Its anhydride group readily reacts with nucleophiles such as amines, enabling efficient acylation under mild conditions. The trifluoroacetamido group stabilizes intermediates and enhances stereocontrol during ring-opening reactions. Commonly employed in pharmaceutical synthesis where enantiomeric purity is critical, especially in the production of bioactive molecules and protease inhibitors. Also serves as a building block in the development of chiral catalysts and ligands due to its rigid stereochemistry and reactive functionality.