(R)-(−)-N-[1-(1-Naphthyl)ethyl]phthalamic acid
98%
science Other reagents with same CAS 163438-05-9
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Used as a chiral derivatizing agent in the resolution of enantiomers, particularly in high-performance liquid chromatography (HPLC). It enables the separation and analysis of racemic mixtures by forming diastereomeric derivatives that differ in their chromatographic behavior. Commonly applied in pharmaceutical research for determining enantiomeric purity and studying stereoselective reactions. Its bulky naphthyl group enhances stereodiscrimination, making it effective for resolving chiral amines and amino compounds. Also utilized in asymmetric synthesis as a chiral auxiliary to control stereochemistry during key bond-forming steps.
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