(R)-(−)-N-[1-(1-Naphthyl)ethyl]phthalamic acid
98%
Reagent
Code: #231934
CAS Number
163438-05-9
blur_circular Chemical Specifications
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Molecular Information
Weight
319.35 g/mol
Formula
C₂₀H₁₇NO₃
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Registry Numbers
MDL Number
MFCD00192338
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Storage & Handling
Storage
Room temperature, seal, dry
description Product Description
Used as a chiral derivatizing agent in the resolution of enantiomers, particularly in high-performance liquid chromatography (HPLC). It enables the separation and analysis of racemic mixtures by forming diastereomeric derivatives that differ in their chromatographic behavior. Commonly applied in pharmaceutical research for determining enantiomeric purity and studying stereoselective reactions. Its bulky naphthyl group enhances stereodiscrimination, making it effective for resolving chiral amines and amino compounds. Also utilized in asymmetric synthesis as a chiral auxiliary to control stereochemistry during key bond-forming steps.
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