Used in chiral resolution to separate enantiomers of basic organic compounds, especially amines. Its ability to form diastereomeric salts with racemic mixtures allows for the isolation of optically active compounds through selective crystallization. Commonly employed in pharmaceutical synthesis for obtaining enantiomerically pure intermediates. Also utilized as a chiral derivatizing agent in analytical chemistry to determine enantiomeric purity. The monohydrate form enhances stability and reproducibility in crystallization processes.