(±)-α-Methoxy-α-trifluoromethylphenylacetic acid
≥95%
Reagent
Code: #205094
Alias
(±)-α-methoxy-α-(trifluoromethyl)phenylacetic acid
CAS Number
81655-41-6
blur_circular Chemical Specifications
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Molecular Information
Weight
234.17 g/mol
Formula
C₁₀H₉F₃O₃
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Registry Numbers
MDL Number
MFCD00066637
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Physical Properties
Melting Point
41-46 °C(lit.)
Boiling Point
95-98 °C0.05 mm Hg(lit.)
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Storage & Handling
Storage
2~8°C, dry, inert gas, light-proof
description Product Description
Widely used in organic synthesis as a chiral derivatizing agent for the separation and analysis of enantiomers. Its ability to form diastereomeric esters with chiral alcohols or amines allows for effective resolution via chromatography or crystallization. Commonly applied in the pharmaceutical industry to determine enantiomeric purity of active ingredients. Also employed in NMR spectroscopy to analyze stereochemistry due to distinct chemical shifts it induces in diastereomeric complexes. Preferred for its strong fluorine signal, enhancing detection sensitivity in 19F NMR studies.
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