Used as a chiral catalyst in the Shi asymmetric epoxidation, enabling highly enantioselective epoxidation of allylic alcohols. It helps control stereochemistry in the formation of epoxides, which are valuable intermediates in pharmaceuticals and fine chemicals. The methyl variant offers improved selectivity, making it ideal for complex molecule synthesis, including natural products and active pharmaceutical ingredients. Widely applied in research and industrial settings for efficient, predictable chiral center formation.