This chiral compound, (1R,3R,4S)-p-Menthane-3-carboxylic acid, serves as a key intermediate in the synthesis of cooling agents, particularly N-substituted p-menthane-3-carboxamides (e.g., WS-3), which provide a refreshing cooling sensation without the minty odor or trigeminal stimulation of menthol. These derivatives are widely used in cosmetics, personal care products such as toothpaste and mouthwash, topical analgesics, and pharmaceuticals for their soothing and cooling effects. It is not typically used directly for its aroma but rather for producing optically active compounds in chiral organic synthesis.