1,2-Cyclopropanedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (1R,2S)-rel-
97%
Reagent
Code: #156599
CAS Number
202212-68-8
blur_circular Chemical Specifications
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Molecular Information
Weight
186.2045 g/mol
Formula
C₉H₁₄O₄
thermostat
Physical Properties
Boiling Point
280.8±33.0 °C(Predicted)
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Storage & Handling
Density
1.219±0.06 g/cm3(Predicted)
Storage
2-8°C, sealed, dry
description Product Description
Used as a chiral building block in the synthesis of pharmaceuticals and biologically active compounds. Its rigid cyclopropane ring and defined stereochemistry make it valuable for developing enantioselective drugs, particularly in the design of enzyme inhibitors and receptor modulators. The tert-butyl ester group enhances lipophilicity and stability during synthetic transformations, allowing for selective protection and deprotection strategies in multi-step organic syntheses. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies due to its conformational constraint and ability to influence molecular geometry.
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