(4S,5R)-3-tert-Butyl 5-methyl 2-(4-methoxyphenyl)-4-phenyloxazolidine-3,5-dicarboxylate
98%
Reagent
Code: #237000
CAS Number
670254-71-4
blur_circular Chemical Specifications
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Molecular Information
Weight
413.46 g/mol
Formula
C₂₃H₂₇NO₆
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Storage & Handling
Storage
2-8°C, dry
description Product Description
Used as a chiral auxiliary in asymmetric synthesis, particularly in enantioselective carbon-carbon bond-forming reactions. Its rigid oxazolidine core and stereodefined centers help control the stereochemistry of reactions such as aldol additions, alkylations, and Diels-Alder cyclizations. The 4-methoxyphenyl and phenyl substituents enhance steric and electronic differentiation, improving diastereoselectivity. After serving its purpose, the auxiliary can be cleaved under mild conditions, leaving the desired chiral product with high enantiomeric purity. Commonly employed in the synthesis of complex natural products and pharmaceutical intermediates where precise stereocontrol is critical.
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