(1S)-(-)-Camphanic chloride is widely used in organic synthesis as a chiral derivatizing agent. It is particularly valuable in the resolution of racemic mixtures, enabling the separation of enantiomers for analytical and preparative purposes. This compound is also employed in the preparation of chiral auxiliaries and catalysts, which are crucial in asymmetric synthesis to produce enantiomerically pure compounds. Additionally, it finds application in the synthesis of biologically active molecules, such as pharmaceuticals, where stereochemistry plays a critical role in efficacy and safety. Its use extends to the modification of natural products and the creation of complex molecular architectures with defined stereochemistry.