(S)-2-Amino-3-(4-(trifluoromethyl)phenyl)propan-1-ol
98%
Reagent
Code: #236508
CAS Number
153181-07-8
science Other reagents with same CAS 153181-07-8
blur_circular Chemical Specifications
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Molecular Information
Weight
219.20 g/mol
Formula
C₁₀H₁₂F₃NO
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Registry Numbers
MDL Number
MFCD17171136
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Physical Properties
Boiling Point
321.1±37.0 °C(Predicted)
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Storage & Handling
Density
1.261±0.06 g/cm3(Predicted)
Storage
Room temperature, dry, light-proof
description Product Description
Used as a chiral intermediate in the synthesis of biologically active compounds, particularly in pharmaceuticals targeting central nervous system disorders. Its structure supports the development of agents with enhanced selectivity and binding affinity due to the presence of both amino and hydroxyl functional groups in a stereochemically defined arrangement. Commonly employed in the preparation of serotonin and norepinephrine reuptake inhibitors, where the (S)-configuration is critical for optimal pharmacological activity. Also utilized in the design of enzyme inhibitors where the trifluoromethylphenyl moiety contributes to metabolic stability and improved lipophilicity.
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