tert-Butyl (cis-3-hydroxycyclobutyl)carbamate
97%
Reagent
Code: #146163
CAS Number
389890-43-1
blur_circular Chemical Specifications
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Molecular Information
Weight
187.24 g/mol
Formula
C₉H₁₇NO₃
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Storage & Handling
Storage
2-8°C
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of biologically active molecules where a protected cyclobutylamine scaffold is required. The tert-butyl carbamate (Boc) group provides stability during multi-step reactions and can be easily removed under mild acidic conditions, allowing for further functionalization. The cis-hydroxy substituent on the cyclobutane ring offers a handle for additional derivatization, making this compound valuable in medicinal chemistry for constructing constrained ring systems that can enhance potency, selectivity, or metabolic stability in drug candidates. Commonly employed in the preparation of kinase inhibitors, CNS-active agents, and other small-molecule therapeutics.
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