Used in peptide synthesis as a chiral building block for the preparation of constrained dipeptide mimetics. Its rigid indane scaffold helps stabilize specific peptide conformations, making it valuable in drug design for enhancing metabolic stability and receptor selectivity. Commonly employed in solid-phase synthesis where the Fmoc group allows for orthogonal protection strategies. Also utilized in the development of protease inhibitors and bioactive molecule scaffolds due to its ability to mimic natural amino acid geometry while introducing structural constraint.