(R)-1-(Naphthalen-1-Yl)-N-(3-(Trifluoromethyl)Benzyl)Ethan-1-Amine
98%
Reagent
Code: #231668
CAS Number
1229512-52-0
blur_circular Chemical Specifications
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Molecular Information
Weight
329.36 g/mol
Formula
C₂₀H₁₈F₃N
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Storage & Handling
Storage
Room temperature
description Product Description
Used as a chiral intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) active compounds. Its structure supports binding affinity to certain neurotransmitter receptors, making it valuable in the research of antidepressants and antipsychotics. The presence of trifluoromethyl and naphthyl groups enhances metabolic stability and lipophilicity, which improves blood-brain barrier penetration. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies targeting G-protein coupled receptors (GPCRs).
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