Used as a selective complexing agent for lithium ions in analytical chemistry and separation processes. Its small cavity size makes it ideal for forming stable complexes with small cations, especially Li⁺, enabling applications in lithium recovery and sensor development. Employed in phase-transfer catalysis to enhance reaction rates in organic synthesis by solubilizing metal ions in nonpolar solvents. Also utilized in the design of ion-selective electrodes and electrochemical devices where lithium ion recognition is required.