(E)-4'-Methylchalcone is widely studied for its potential applications in the field of medicinal chemistry. It exhibits significant biological activities, including anti-inflammatory, anticancer, and antioxidant properties. Research has shown that it can inhibit the growth of various cancer cells by inducing apoptosis and suppressing tumor progression. Additionally, it is being explored for its role in managing inflammatory diseases due to its ability to modulate key signaling pathways. In the pharmaceutical industry, it serves as a promising lead compound for the development of novel therapeutic agents. Furthermore, its antioxidant properties make it a potential candidate for use in skincare and cosmetic products to protect against oxidative stress and aging.