Mevastatin
≥96%(HPLC)
science Other reagents with same CAS 73573-88-3
blur_circular Chemical Specifications
description Product Description
Mevastatin is primarily used in the study and treatment of hypercholesterolemia, a condition characterized by high levels of cholesterol in the blood. It functions as an inhibitor of HMG-CoA reductase, an enzyme crucial for cholesterol synthesis in the liver. By blocking this enzyme, Mevastatin effectively reduces the production of cholesterol, thereby lowering the overall cholesterol levels in the bloodstream. This mechanism makes it a valuable tool in preventing cardiovascular diseases, which are often linked to high cholesterol levels. Additionally, Mevastatin is utilized in research to understand the biochemical pathways involved in cholesterol metabolism and to develop more effective cholesterol-lowering drugs. Its role in inhibiting cell proliferation also makes it a subject of interest in cancer research, particularly in studies exploring the relationship between cholesterol metabolism and cancer cell growth.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Melting point | 151-155 |
| Purity (HPLC) | 96-100% |
| Specific Rotation (20°C, c=0.4, Acetone) | 275-285 |
| Appearance | White to light yellow powder |
| Proton NMR Spectrum | Conforms to Structure |
| Solubility | Colorless and clear (25 mg/mL, EtOH) |
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