1-Cyano-2-methyl-1-[2-(5-methylimidazol-4-yl-methylthio)ethyl]isothiourea

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Reagent Code: #80087
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CAS Number 52378-40-2

science Other reagents with same CAS 52378-40-2

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 269.38 g/mol
Formula C₁₀H₁₆N₆S₂
badge Registry Numbers
MDL Number MFCD27966891
thermostat Physical Properties
Melting Point 148-150 °C (lit.)
inventory_2 Storage & Handling
Storage 2-8°C, dark, dry

description Product Description

This compound serves as a crucial intermediate in the synthesis of famotidine, a histamine H2-receptor antagonist used for treating conditions like peptic ulcers and gastroesophageal reflux disease (GERD). It is primarily employed in medicinal chemistry and pharmaceutical research to develop drugs that inhibit gastric acid secretion. The molecule's structure, featuring cyano, isothiourea, and imidazole moieties, enables the formation of bioactive thioamide linkages essential for H2 blocker activity. Researchers utilize it in the design of related therapeutic agents targeting acid-related disorders, with potential extensions to modulating inflammatory responses in the gastrointestinal tract.

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Size Availability Unit Price Quantity
inventory 5g
10-20 days ฿522.00
inventory 25g
10-20 days ฿1,800.00
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1-Cyano-2-methyl-1-[2-(5-methylimidazol-4-yl-methylthio)ethyl]isothiourea
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This compound serves as a crucial intermediate in the synthesis of famotidine, a histamine H2-receptor antagonist used for treating conditions like peptic ulcers and gastroesophageal reflux disease (GERD). It is primarily employed in medicinal chemistry and pharmaceutical research to develop drugs that inhibit gastric acid secretion. The molecule's structure, featuring cyano, isothiourea, and imidazole moieties, enables the formation of bioactive thioamide linkages essential for H2

This compound serves as a crucial intermediate in the synthesis of famotidine, a histamine H2-receptor antagonist used for treating conditions like peptic ulcers and gastroesophageal reflux disease (GERD). It is primarily employed in medicinal chemistry and pharmaceutical research to develop drugs that inhibit gastric acid secretion. The molecule's structure, featuring cyano, isothiourea, and imidazole moieties, enables the formation of bioactive thioamide linkages essential for H2 blocker activity. Researchers utilize it in the design of related therapeutic agents targeting acid-related disorders, with potential extensions to modulating inflammatory responses in the gastrointestinal tract.

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