Low-Substituted Hydroxypropyl cellulose
CHP, hydroxypropoxyl: 5.0-16.0%
science Other reagents with same CAS 9004-64-2
blur_circular Chemical Specifications
description Product Description
Low-Substituted Hydroxypropyl Cellulose (L-HPC) is primarily used as a disintegrant and binder in pharmaceutical tablets, enhancing compressibility, mechanical strength, and rapid disintegration properties without significantly affecting dissolution. It is also employed in direct compression formulations to improve powder flow and tablet integrity. Due to its low degree of substitution, it is not typically used as a thickener or film-former like higher-substituted HPC variants, limiting its application mainly to oral solid dosage forms in pharmaceuticals. It may have niche uses in some controlled-release systems as a matrix component, but food, cosmetic, and ophthalmic applications are more common for standard HPC.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| pH (5 in H2O) | 5-7.5 |
| Loss on Drying | 8 |
| Hydroxypropyl | 5-16 |
| Appearance | White to off-white powder |
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