Low-Substituted Hydroxypropyl cellulose

Hydroxypropoxy: 10%-12.9%

Reagent Code: #65832
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Alias 2-hydroxypropyl ether cellulose; LH -11
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CAS Number 9004-64-2

science Other reagents with same CAS 9004-64-2

blur_circular Chemical Specifications

badge Registry Numbers
MDL Number MFCD00132688
inventory_2 Storage & Handling
Density 0.5 g/mL at 25 °C(lit.)
Storage room temperature

description Product Description

Low-Substituted Hydroxypropyl Cellulose (L-HPC) is primarily utilized in the pharmaceutical industry as a superdisintegrant in tablet and capsule formulations. Its low degree of substitution (typically 7-12% hydroxypropyl content) renders it water-insoluble but capable of rapid swelling upon hydration, which facilitates quick tablet disintegration and enhances the dissolution rate of poorly soluble active pharmaceutical ingredients, thereby improving bioavailability. Unlike standard Hydroxypropyl Cellulose, L-HPC is not commonly used as a binder or film-coating agent due to its limited solubility and film-forming properties. It is biocompatible, non-toxic, and suitable for oral dosage forms. Applications in food or cosmetics are limited, as it is optimized for pharmaceutical disintegration rather than thickening or emulsification.

format_list_bulleted Product Specification

Test Parameter Specification
pH (5 in H2O) 5.0-7.5
Loss on Drying 0-5.0%
Hydroxypropyl 10.0-12.9%
Appearance White to Off-white Powder
Infrared Spectrum Conforms to Structure

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 500g
10-20 days ฿5,880.00
inventory 100g
10-20 days ฿2,280.00
inventory 2.5kg
10-20 days ฿19,880.00

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Low-Substituted Hydroxypropyl cellulose
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Low-Substituted Hydroxypropyl Cellulose (L-HPC) is primarily utilized in the pharmaceutical industry as a superdisintegrant in tablet and capsule formulations. Its low degree of substitution (typically 7-12% hydroxypropyl content) renders it water-insoluble but capable of rapid swelling upon hydration, which facilitates quick tablet disintegration and enhances the dissolution rate of poorly soluble active pharmaceutical ingredients, thereby improving bioavailability. Unlike standard Hydroxypropyl Cellulo

Low-Substituted Hydroxypropyl Cellulose (L-HPC) is primarily utilized in the pharmaceutical industry as a superdisintegrant in tablet and capsule formulations. Its low degree of substitution (typically 7-12% hydroxypropyl content) renders it water-insoluble but capable of rapid swelling upon hydration, which facilitates quick tablet disintegration and enhances the dissolution rate of poorly soluble active pharmaceutical ingredients, thereby improving bioavailability. Unlike standard Hydroxypropyl Cellulose, L-HPC is not commonly used as a binder or film-coating agent due to its limited solubility and film-forming properties. It is biocompatible, non-toxic, and suitable for oral dosage forms. Applications in food or cosmetics are limited, as it is optimized for pharmaceutical disintegration rather than thickening or emulsification.

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