Low-Substituted Hydroxypropyl cellulose
Hydroxypropoxy: 10%-12.9%
science Other reagents with same CAS 9004-64-2
blur_circular Chemical Specifications
description Product Description
Low-Substituted Hydroxypropyl Cellulose (L-HPC) is primarily utilized in the pharmaceutical industry as a superdisintegrant in tablet and capsule formulations. Its low degree of substitution (typically 7-12% hydroxypropyl content) renders it water-insoluble but capable of rapid swelling upon hydration, which facilitates quick tablet disintegration and enhances the dissolution rate of poorly soluble active pharmaceutical ingredients, thereby improving bioavailability. Unlike standard Hydroxypropyl Cellulose, L-HPC is not commonly used as a binder or film-coating agent due to its limited solubility and film-forming properties. It is biocompatible, non-toxic, and suitable for oral dosage forms. Applications in food or cosmetics are limited, as it is optimized for pharmaceutical disintegration rather than thickening or emulsification.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| pH (5 in H2O) | 5.0-7.5 |
| Loss on Drying | 0-5.0% |
| Hydroxypropyl | 10.0-12.9% |
| Appearance | White to Off-white Powder |
| Infrared Spectrum | Conforms to Structure |
shopping_cart Available Sizes & Pricing
Cart
No products