Oxaliplatin is widely used in the treatment of colorectal cancer, particularly in combination with other chemotherapy agents like 5-fluorouracil and leucovorin. This combination, known as FOLFOX, is a standard regimen for both advanced and early-stage colorectal cancer. It is also employed in the treatment of other cancers, such as gastric and pancreatic cancers, though its primary application remains in colorectal cancer management. The drug works by inhibiting DNA replication and transcription, leading to cancer cell death. Its use is often limited by side effects, including neuropathy, which requires careful patient monitoring and dose adjustments.