Valpromide is primarily used as an anticonvulsant in the treatment of epilepsy, particularly for managing complex partial seizures and generalized seizures. It is also employed as a mood stabilizer in bipolar disorder, helping to control manic episodes and prevent mood swings. Additionally, valpromide has shown potential in alleviating neuropathic pain and migraine prophylaxis due to its ability to modulate neurotransmitter activity. In some cases, it is utilized off-label for anxiety disorders and as an adjunct therapy in schizophrenia to manage agitation and aggression. Its sedative properties make it useful in calming severe agitation in certain psychiatric conditions.