Sertraline hydrochloride (CAS 79559-97-0) is the hydrochloride salt of sertraline, a selective serotonin reuptake inhibitor (SSRI) used as an active pharmaceutical ingredient (API) in antidepressants. It is applied in the manufacture of medications for major depressive disorder, obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD), social anxiety disorder, and premenstrual dysphoric disorder (PMDD). This specialty chemical is supplied as a white to off-white solid, ≥98% purity (HPLC), melting point 240-250°C, specific rotation [²⁰_D] +35 to +41° (c=2, MeOH), suitable for pharmaceutical research, development, and manufacturing.