1,2,4-Triazole is widely used in the pharmaceutical industry as a key building block for the synthesis of various drugs, particularly antifungal and antiviral medications. It serves as a core structure in compounds like fluconazole and itraconazole, which are effective against fungal infections. Additionally, it is utilized in the development of agrochemicals, including herbicides and plant growth regulators, due to its ability to inhibit specific enzymes in pests and weeds. In material science, 1,2,4-triazole derivatives are incorporated into polymers and coatings to enhance their thermal stability and corrosion resistance. Its versatility also extends to coordination chemistry, where it acts as a ligand in the creation of metal-organic frameworks (MOFs) for catalytic and storage applications.