Used primarily in the treatment and prevention of HIV infection. It is a key component in antiretroviral therapy, helping to reduce the amount of virus in the body, thereby improving immune function and reducing the risk of HIV-related complications. Also effective in treating chronic hepatitis B infection. Its prodrug design enhances oral absorption, allowing for better delivery and conversion to the active form within cells. Widely used in combination with other antiretrovirals in single-tablet regimens for easier patient compliance. Employed in pre-exposure prophylaxis (PrEP) to lower the risk of acquiring HIV in high-risk individuals.