Tioconazole is primarily used as an antifungal agent in the treatment of various fungal infections. It is commonly formulated in topical preparations for skin, nail, and mucosal infections. One of its main applications is in the treatment of cutaneous fungal infections such as athlete’s foot, jock itch, and ringworm due to its ability to inhibit fungal cell membrane synthesis. It is also used in vaginal creams and suppositories for the treatment of vulvovaginal candidiasis, offering localized action with minimal systemic absorption. In dermatology, tioconazole is valued for its broad-spectrum activity against dermatophytes, yeasts, and molds. Its efficacy in nail infections, especially onychomycosis, is enhanced in nail lacquers or solutions that allow penetration into the nail bed. Due to its lipophilic nature, tioconazole penetrates skin and keratinized tissues effectively, making it suitable for infections involving nails and scalp. It is often preferred for short-course therapy because of its persistent antifungal activity even after discontinuation.