Used in blood collection tubes to prevent clotting by binding calcium ions, enabling accurate hematological testing. Commonly found in blue-top tubes for coagulation assays like PT and aPTT. Also utilized in blood transfusion bags to preserve blood by inhibiting coagulation during storage. Employed in medical procedures involving extracorporeal circulation, such as dialysis and cardiopulmonary bypass, to maintain blood flow without clot formation. Additionally, acts as an anticoagulant in laboratory settings for preparing plasma samples.