Used primarily in the management of type 2 diabetes mellitus, this compound helps improve glycemic control by increasing insulin sensitivity in peripheral tissues such as muscle and adipose tissue. It acts as an agonist for peroxisome proliferator-activated receptor gamma (PPAR-γ), which regulates genes involved in glucose and lipid metabolism. It is typically prescribed as an adjunct to diet and exercise, often in combination with other antidiabetic agents like metformin or insulin. Its use may lead to improved HbA1c levels and reduced fasting plasma glucose. However, due to potential cardiovascular risks and effects on fluid retention, its application is often limited to patients without a history of heart failure and under careful medical supervision.