Used as a reference standard in pharmaceutical research and quality control for the analysis of raloxifene metabolism. It serves as a key metabolite in studying the metabolic pathways of raloxifene in the liver, particularly in investigations involving cytochrome P450 enzymes. Commonly employed in bioanalytical assays such as LC-MS/MS to validate detection methods and quantify metabolite formation in human plasma or urine. Also utilized in pharmacokinetic and drug interaction studies to assess the safety and efficacy of raloxifene-containing medications.