Used in skincare products for its anti-inflammatory and analgesic properties, helping to soothe irritated skin and reduce redness. Commonly found in topical formulations for muscle and joint pain relief due to its counterirritant effect, which creates a warming sensation and improves local blood circulation. Also utilized in cosmetic treatments to enhance the penetration of other active ingredients through the skin. In research settings, it serves as a metabolite and derivative in studies related to niacin metabolism and skin absorption.