Used topically as an antibiotic in the treatment of acne vulgaris. It works by inhibiting bacterial protein synthesis, targeting Propionibacterium acnes, a key contributor to inflammatory acne lesions. Its formulation in sulfosalicylate salt enhances stability and skin penetration. Commonly found in creams, gels, or lotions, it helps reduce both the number and severity of acne breakouts. Due to its localized action, it minimizes systemic absorption, lowering the risk of side effects. Often prescribed as part of combination therapy with other acne treatments for improved efficacy.