Ketoconazole

2mM in DMSO

Reagent Code: #201400
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CAS Number 65277-42-1

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 531.43 g/mol
Formula C₂₆H₂₈Cl₂N₄O₄
badge Registry Numbers
EC Number 265-667-4
MDL Number MFCD00058579
thermostat Physical Properties
Melting Point 148-152 °C
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used primarily as an antifungal agent, this chemical is effective in treating a variety of fungal infections of the skin, including athlete’s foot, jock itch, ringworm, and seborrheic dermatitis. It works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, thereby disrupting membrane integrity and leading to cell death. It is commonly formulated in topical preparations such as creams, gels, foams, and shampoos for localized treatment. In more severe or systemic fungal infections, it may be administered orally, though this route is less common today due to potential liver toxicity and drug interactions. Also found in medicated shampoos to reduce flaking, itching, and scaling associated with dandruff and scalp conditions. Its anti-inflammatory properties contribute to symptom relief in certain dermatological disorders. Due to its ability to interfere with steroid synthesis, it has been used off-label in the management of Cushing’s syndrome and certain hormonal skin conditions like androgenetic alopecia, although alternative agents are often preferred now.

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Size Availability Unit Price Quantity
inventory 1ml
10-20 days ฿4,890.00

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