Fenbuconazole is widely used as a systemic fungicide in agriculture, particularly for controlling a broad spectrum of fungal diseases in crops. It is effective against rusts, powdery mildew, leaf spots, and blights in cereals such as wheat, barley, and oats. It is commonly applied as a foliar spray or seed treatment to protect plants during early growth stages. The compound works by inhibiting ergosterol biosynthesis, a key component of fungal cell membranes, leading to the disruption of fungal growth and reproduction. Due to its long residual activity and strong penetration into plant tissues, it provides extended protection even under high disease pressure. Fenbuconazole is also used in horticulture on fruits, vegetables, and ornamental plants to manage diseases like apple scab and grape downy mildew. Its systemic nature allows it to move within the plant, offering both preventive and curative action. It is often included in integrated pest management programs to reduce reliance on contact fungicides and to manage resistance development in pathogen populations.