Ezetimibe is primarily used to lower elevated levels of low-density lipoprotein (LDL) cholesterol in the blood. It works by inhibiting the absorption of cholesterol in the small intestine, which leads to a reduction in circulating LDL cholesterol. It is commonly prescribed as an adjunct to diet and exercise and is often used alongside statins for enhanced cholesterol-lowering effects. Ezetimibe is beneficial in managing conditions such as hypercholesterolemia and atherosclerosis, helping reduce the risk of cardiovascular events like heart attacks and strokes. It is also used in patients with inherited lipid disorders, such as homozygous familial hypercholesterolemia, to provide additional control over cholesterol levels when statins alone are insufficient.